By State · SAMHSA-verified directory
Addiction treatment in South Carolina
201 verified treatment centers across South Carolina. Overdose rate 30.8 per 100,000 (CDC 2023) · Medicaid not expanded.
201
Centers
20
Cities
Not expanded
Medicaid
24/7
Helpline
Treatment centers in South Carolina
Every listing sourced from SAMHSA Treatment Services Locator.
Orangeburg County Mental Health Holly Hill Mental Health Clinic
Holly Hill, SC
The Carolina Center
Greer, SC
Marshall I Pickens Hospital Greenville Memorial Medical Campus
Greenville, SC
Recovery Unplugged Nashville
North Charleston, SC
Colleton Medical Center Walterboro
Walterboro, SC
Cornerstone Abbeville
Abbeville, SC
BHG Aiken Treatment Center
Aiken, SC
Pee Dee Mental Health Center Florence County Clinic
Florence, SC
Greater Greenville Mental Health Simpsonville Clinic
Simpsonville, SC
Recovery Unplugged South Carolina
North Charleston, SC
Dallas Sober Living Solutions Highlands - Women
Florence, SC
Santee/Wateree Mental Health Center Clarendon County Clinic
Manning, SC
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Cities in South Carolina with verified facilities
20 cities. Click through for city-specific listings.
North Charleston
23 centers
Darlington
13 centers
Florence
11 centers
North Myrtle Beach
9 centers
Greenville
9 centers
Seneca
8 centers
Columbia
7 centers
Charleston
7 centers
Aiken
6 centers
Varnville
5 centers
Greenwood
5 centers
Conway
5 centers
Chesterfield
5 centers
Sumter
4 centers
Lexington
4 centers
Gaffney
4 centers
Spartanburg
3 centers
Rock Hill
3 centers
Orangeburg
3 centers
Newberry
3 centers
Understanding treatment in South Carolina
South Carolina has 201 SAMHSA-verified treatment facilities spread across the Southeast. The practical task of choosing among them is less about information volume (every center has a website) and more about the right filter. The paragraphs below provide that filter.
The Medicaid question
Regarding public coverage in South Carolina: South Carolina has not expanded Medicaid under the Affordable Care Act. The significance is structural — typically falls into the eligibility gap — income too high for traditional Medicaid, too low to qualify for substantial Marketplace subsidies, and that fact ripples into facility-level economics, charity-care availability, and the real network a patient can access.
The overdose-mortality context
The overdose rate in South Carolina runs 30.8 per 100,000 residents (CDC 2023). That number is a useful input, not a verdict — it reflects the scale of the local crisis and helps calibrate urgency. Medicaid eligibility gap combined with rural provider shortage Treatment-planning decisions work backward from what the local epidemiology implies.
How access actually works in South Carolina
Access in South Carolina is more uneven than aggregate data suggests. Medicaid eligibility gap combined with rural provider shortage For a patient trying to narrow the 201 facility list to 3-5 candidates, the practical filter is: (1) in-network status with your specific plan product; (2) ASAM-aligned level-of-care match; (3) MAT policy for opioid use disorder. Anything less than all three leaves gaps.
What to do next
The most productive next step in South Carolina is usually an outside clinical assessment — a primary-care doctor, a licensed substance-use counselor, or the SAMHSA National Helpline (1-800-662-HELP). The assessment clarifies what level of care is actually warranted, which is the foundation for everything that follows.
Last updated April 2026. Sources: SAMHSA Treatment Locator, CDC WONDER (overdose mortality 2023), KFF Medicaid Tracker, ASAM Criteria 4e. See our editorial policy.